A Platform to Study Platelet Aggregation and Thrombus Growth Based on Dynamic Stress
F. J. Tovar-Lopeza1, G. Rosengarten2, K. Khoshmanesh3 , E. Westein4 , S. P. Jackson4, Arnan Mitchell 1, and W. S. Nesbitt4,
1: School of Electrical and Computer Engineering, RMIT University, Melbourne, VIC 3001, Australia; 2: School of Mechanical and Manufacturing Engineering, The University of New South Wales UNSW, Sydne
Date Posted: Tuesday, June 22, 2010
We present a microfluidic device that is able to trigger initial recruitment and subsequent aggregation of discoid platelets by mimicking the effects of pathological changes in blood vessel geometry.
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